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Rheumatic Diseases

In the CRADLE study, Megan E.B. Clowse, MD, Associate Professor of Medicine, Duke University School of Medicine, Durham, NC, and colleagues, evaluated the concentrations of certo­lizumab pegol in mature breast milk of patients receiving this biologic, and calculated the average daily dose of certo­lizumab pegol potentially ingested by infants being breastfed.

“Over the years, numerous observational studies have associated patients with RA with the increased risk of osteoporosis fracture involving mainly the hip or vertebral. However, most clinical studies performed are either limited in sample size, restricted to certain subpopulation, or are fracture-site specific.

Results from a recent study suggest that working in certain occupations may increase a worker’s risk for rheumatoid arthritis (RA), even after adjustment for lifestyle-related factors, including smoking, alcohol use, education level, and obesity (Ilar A, et al. Arthritis Care Res (Hoboken). 2017 Aug 10. Epub ahead of print).

“The objectives of the study were to determine whether hospital admission with an autoimmune disease is associated with future admission with dementia more often than expected by chance,” the research explained.

Hypermobility syndrome represents a complex clinical picture that is often neglected by health professionals, said Rodney Grahame, MD, Consultant Rheumatologist, The Hypermobility Unit at the Hospital of St. John and St. Elizabeth, London, England, at the 9th Annual Rheumatology Nurses Society Conference.
Up to 40% of patients with rheumatic diseases will have neuropathies attributable to competing disorders. These competing comorbidities may encapsulate many different syndromes. Using the VITAMINS mnemonic may help to distinguish between neuropathies caused by rheumatic diseases versus those caused by competing morbidities, said Julius Birnbaum, MD, Assistant Professor of Medicine and Neurology, The Johns Hopkins Hospital, Baltimore, MD, at the 9th Annual Rheumatology Nurses Society Conference.

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