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VBCR - August 2015, Volume 4, No 4 - Value Propositions

The frequency of pulmonary involvement in ankylosing spondylitis (AS) ranges from 20% to 57% when assessed using spirometry and from 40% to 80% when using high-resolution computed tomography. At the annual meeting of the European League Against Rheumatism in Rome, Razvan Dragoi, MD, PhD, Victor Babes University of Medicine and Pharmacy, Timișoara, Romania, reported on a study designed to evaluate the impact of inspiratory muscle training (IMT) on aerobic capacity and pulmonary function in patients with AS. Standard muscular rehabilitation exercise combined with IMT significantly improved lung function in these patients.

Dragoi and colleagues studied 54 male patients with AS, aged 47.8 ± 6.8 years, who were randomized to receive either conventional rehabilitation exercise training plus IMT, or conventional rehabilitation exercise training only. Before and after the training program, all patients received pulmonary function testing and cardiopulmonary exercise testing. Conventional training comprised a 40-minute weekly group session and instructions to complete 40-minute sessions 5 days a week at home. The investigational group added supervised IMT using a computer-assisted device 3 times per week for 24 sessions.

After 8 weeks of IMT plus standard rehabilitation exercise, patients with AS had increased chest expansion, better aerobic capacity and resting pulmonary function, and improved ventilatory efficiency when compared with those patients who performed conventional exercise training only. The researchers concluded that IMT is a feasible treatment option in patients who experience pulmonary dysfunction due to AS. Dragoi R, et al. Ann Rheum Dis. 2015;74(suppl 2):135. Abstract OP0173.

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Last modified: August 26, 2015
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