Paracetamol (acetaminophen in the United States) appears to have more cardiovascular, gastrointestinal (GI), and renal toxicity, as well as increased risk of mortality, than has been previously assumed, especially at high doses, according to a systematic review of the literature published online.
Hepatitis B virus (HBV) reactivation is a serious and potentially lethal complication of HBV infection, and the risk is increased in patients on immunosuppressive therapy, especially anti–tumor necrosis factor (TNF) inhibitors or TNF-like antirheumatic drugs used by patients with rheumatoid arthritis (RA) and other rheumatic diseases.
The most comprehensive database in the United States on total hip and knee joint replacements (TJRs) and outcomes establishes benchmarks for these surgeries and offers new insights into appropriateness criteria and timing of surgeries that will enable value-based care.
Granulomatosis with polyangiitis (GPA) is a rare disease characterized most often by inflammation of the small blood vessels of the respiratory system, although the kidneys and other organs may also be affected. GPA is complex, and prompt diagnosis and treatment are necessary to avoid serious complications.
In an earlier study, Tanaka and colleagues found that cost-effectiveness appears to favor tocilizumab (TCZ), a humanized anti-interleukin-6 receptor monoclonal antibody, in comparison with TNF inhibitors in patients with rheumatoid arthritis (RA).
Although patients with rheumatoid arthritis (RA) undergo radiological evaluations, the actual use of radiological imaging in RA has not been adequately reported. A population-based study evaluated the use of radiological procedures in patients with RA compared with patients without RA.
A January 14, 2015, report published by the Institute of Medicine (IOM) walks a fine line between the competing clinical data sharing comfort zones of pharmaceutical companies, physician associations, patient groups, and other advocacy organizations.
The Office of the National Coordinator for Health IT was established in 2004 by executive action. In 2009, Congress authorized the Meaningful Use (MU) program, which offered financial incentives for adopting electronic health records (EHR) and other information technology (IT) tools.
Mortality High, But Relatively Steady, in Patients With Rheumatoid Arthritis Versus General Population
An Ontario, Canada, study has estimated that standardized mortality rates are 41% to 51% higher in people with rheumatoid arthritis (RA) than in the general population, although the rates have been declining since 1997. In 1996-1997 the standardized mortality rate (SMR) among Ontario residents aged 15 years and older who had RA was 1.51, compared with those without RA.
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Results 1 - 10 of 17
Results 1 - 10 of 17