Washington, DC—A chemotherapy–immunotherapy combination has been shown to be extremely effective in a small clinical trial of previously untreated mantle-cell lymphoma, leading to objective responses in every patient, including complete responses in almost 90%, investigators reported at the 2013 American Association for Cancer Research annual meeting.

Washington, DC—Although still in very early-phase testing in humans, the results of 2 small studies in children suggest that reinfusing autologous genetically engineered T cells can reverse acute lymphocytic leukemia (ALL) in children. Both studies were presented at the 2013 American Association for Cancer Research meeting.

All the children had run out of treatment options and were close to death; 2 had a remarkable recovery after T-cell therapy and remain in complete remission.

Washington, DC—A positive fluorodeoxyglucose-positron emission tomography (FDG-PET) scan distinguished patients with high-risk stage I non–small-cell lung cancer (NSCLC) who may benefit from adjuvant chemotherapy, a retrospective review of a large database showed.

Washington, DC—A positive fluorodeoxyglucose-positron emission tomography (FDG-PET) scan distinguished patients with high-risk stage I non–small-cell lung cancer (NSCLC) who may benefit from adjuvant chemotherapy, a retrospective review of a large database showed.

Washington, DC—Lung cancer false- positive rates varied 20-fold across the United States, raising questions about the potential impact on organized screening programs, according to data presented at the 2013 American Association for Cancer Research annual meeting.

Washington, DC—Lung cancer false- positive rates varied 20-fold across the United States, raising questions about the potential impact on organized screening programs, according to data presented at the 2013 American Association for Cancer Research annual meeting.

New Orleans, LA—“Patient engagement” is a healthcare buzz phrase, and a critical part of this concept is patient connectivity to information technology (IT). GetWellNetwork is a patient-focused IT system that aims to empower the patient to improve outcomes in a variety of disease states.

Hollywood, FL—A case management program for terminally ill patients with cancer can reduce cancer-related healthcare costs and extend hospice length of stay, according to an analysis of the Cancer Support Program (CSP) of Optum Health, a health services company, which was presented at the 2013 National Comprehensive Cancer Network® annual conference.

Hollywood, FL—Updates to the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines® were presented at the 2013 NCCN annual conference. The updates were minor for most tumor sites, but new guidelines were introduced for penile cancer and for survivorship.

US oncologists and radiologists are waiting to see whether the Centers for Medicare & Medicaid Services (CMS) will reconsider its proposal to limit the use of and reimbursement for fluorodeoxy­glucose-positron emission tomography (FDG-PET) scan after initial anti­cancer therapy to 1 scan in patients with solid tumors (with the exception of patients with prostate cancer, who will not be reimbursed for any FDG-PET scans).

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