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In the News: Value-Based Care - May 2016

According to the authors of a recent study, although monitoring of anti-drug antibodies (ADAbs) or serum concentrations of biologicals in rheumatoid arthritis treatments could explain efficacy loss, and help with choosing subsequent medication, such monitoring of tumor necrosis factor (TNF)-α blockers is not generally done on a routine basis in current clinical practices. They have, however, demonstrated the cost-benefits of routine monitoring of drug levels and ADAbs in clinical practice, which they report can in turn improve the decision-making process of using TNF-α blockers.
Patients with rheumatoid arthritis who inadequately responded to methotrexate monotherapy and were treated with tocilizumab plus methotrexate experienced subdued radiographic progression and maintained improvements in signs and symptoms over 5 years, according to data from Joel Kremer, MD, Albany Medical College, NY, and colleagues.

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