Knee Osteoarthritis

Chondroitin sulfate was superior to celecoxib in reducing the progression of long-term damage of knee osteoarthritis (OA) in the first randomized trial to demonstrate this. Chondroitin sulfate was safe over a 2-year period, with no significant side effects.
Intra-articular (IA) corticosteroid (CS) injections do not prevent long-term structural damage in patients with knee osteoarthritis (OA), nor do the injections hasten joint damage, according to the results of a National Institutes of Health–funded randomized clinical trial.
Exercise is beneficial for patients with knee osteoarthritis (OA), but few studies have addressed which is the most beneficial and cost-effective strategy.

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